Osteopathic Manipulative Treatment for Headaches: A Comprehensive Review

Headaches affect nearly half the global population and are a leading cause of disability. While traditional treatments—ranging from medications to lifestyle modifications—have been the mainstay, emerging evidence suggests that osteopathic manipulative treatment (OMT) offers a promising complementary approach. This review integrates findings from the past two decades to provide an overview of how OMT can benefit various headache disorders.


Understanding Headache Disorders

Headaches manifest in different forms:

  • Tension-Type Headaches (TTHs):
    Characterized by a dull, aching pain and a feeling of tightness across the head. TTHs are often associated with stress, muscle tension, and poor posture.
  • Migraines:
    These are typically unilateral, pulsating headaches that can last from hours to days and are often accompanied by nausea, sensitivity to light and sound, and, in some cases, an aura.
  • Cervicogenic Headaches (CGHs):
    Secondary headaches that originate from cervical spine dysfunctions. CGHs are usually unilateral, with associated neck pain and reduced range of motion.

Some examples of OMT include:

  • Myofascial Release: Relieves tension in the soft tissues to improve blood flow and reduce pain.
  • Cranial Osteopathy: Focuses on restoring mobility to cranial sutures and improving cerebrospinal fluid flow, which can help alleviate migraines and tension headaches.
  • Muscle Energy Techniques: Engage the patient’s own muscle contractions to reduce hypertonicity, particularly beneficial in managing cervicogenic headaches.

By addressing both peripheral and central sensitization—key contributors to headache disorders—OMT aims to decrease the frequency, intensity, and duration of headache episodes while improving overall quality of life.


Review of the Evidence

A comprehensive literature search across PubMed, MEDLINE, and Google Scholar identified 15 relevant studies involving adult patients with migraine, TTH, or CGH. These studies included randomized controlled trials and observational research, with outcome measures such as:

  • Pain frequency and intensity: Monitored using tools like the Numerical Pain Rating Scale and headache diaries.
  • Disability and Quality of Life: Evaluated with indices such as the Headache Disability Index (HDI) and Headache Impact Test (HIT-6).
  • Functional Assessments: Including cervical range of motion and isometric neck strength.

Key findings from the review include:

  • Tension-Type Headaches: Manual therapies like suboccipital muscle inhibition and cervical mobilization have been shown to reduce pain and improve muscle strength, leading to a decrease in peripheral and central sensitization.
  • Migraines: Techniques such as cranial osteopathy and articulatory methods have resulted in fewer migraine episodes, lower pain intensity, and reduced medication usage, with improvements persisting even one month post-treatment.
  • Cervicogenic Headaches: Spinal manipulation and mobilization of the cervical region have demonstrated significant benefits, with reductions in headache frequency, pain intensity, and overall disability.

Despite promising results, heterogeneity in study design and outcome measures calls for more high-quality, large-scale trials to standardize treatment protocols and confirm these findings.


OMT emerges as a valuable, patient-centered complement to traditional headache management strategies. Its holistic focus on restoring musculoskeletal balance and enhancing fluid dynamics can lead to significant improvements in headache frequency, intensity, and overall quality of life. As research continues to evolve, integrating OMT into multidisciplinary care models may reduce reliance on medications and offer a more comprehensive solution for headache sufferers.

Sharath H, Nadipena P, Qureshi M, et al. (August 05, 2024) A Review on Osteopathic Manipulation in Patients With Headache. Cureus 16(8): e66242. doi:10.7759/cureus.66242

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